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.15showed the variations concerning IT and ID BCG vaccination in rhesus macaques by repeatedly infecting the test population with really reduced doses of Mtb (1 CFU Mtb) to simulate human pure infection. amazingly, an infection of rhesus macaques immunized by endobronchial instillation was significantly delayed, or even entirely absent. In distinct

Robert Koch did not imagine the cattle and human tuberculosis health conditions were being very similar, which delayed the recognition of contaminated milk as being a source of infection. over the 1st 50 percent of your 1900s, the chance of transmission from this source was dramatically reduced after the application with the pasteurization system.